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Index > Protein center > Col2a1(Gene name) > Mouse
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  • Col2a1 (Gene name),
  • Collagen alpha-1(II) chain (Protein name ),  CO2A1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Col2a1;
    Protein name:
    Collagen alpha-1(II) chain;
    Alternative:
    Alpha-1 type II collagen;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homotrimers of alpha 1(II) chains.
    Function:
    Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces.
    Subcellular Location:
    Secreted extracellular space extracellular matrix
    Protein Attributes:
    Sequence length:
    1487
    Sequence:
    50:
    MIRLGAPQSL | VLLTLLIAAV | LRCQGQDAQE | AGSCLQNGQR | YKDKDVWKPS | 
    100:
    SCRICVCDTG | NVLCDDIICE | DPDCLNPEIP | FGECCPICPA | DLATASGKLG | 
    150:
    PKGQKGEPGD | IRDIIGPRGP | PGPQGPAGEQ | GPRGDRGDKG | EKGAPGPRGR | 
    200:
    DGEPGTPGNP | GPAGPPGPPG | PPGLSAGNFA | AQMAGGYDEK | AGGAQMGVMQ | 
    250:
    GPMGPMGPRG | PPGPAGAPGP | QGFQGNPGEP | GEPGVSGPMG | PRGPPGPAGK | 
    300:
    PGDDGEAGKP | GKSGERGLPG | PQGARGFPGT | PGLPGVKGHR | GYPGLDGAKG | 
    350:
    EAGAPGVKGE | SGSPGENGSP | GPMGPRGLPG | ERGRTGPAGA | AGARGNDGQP | 
    400:
    GPAGPPGPVG | PAGGPGFPGA | PGAKGEAGPT | GARGPEGAQG | SRGEPGNPGS | 
    450:
    PGPAGASGNP | GTDGIPGAKG | SAGAPGIAGA | PGFPGPRGPP | GPQGATGPLG | 
    500:
    PKGQAGEPGI | AGFKGDQGPK | GETGPAGPQG | APGPAGEEGK | RGARGEPGGA | 
    550:
    GPIGPPGERG | APGNRGFPGQ | DGLAGPKGAP | GERGPSGLTG | PKGANGDPGR | 
    600:
    PGEPGLPGAR | GLTGRPGDAG | PQGKVGPSGA | PGEDGRPGPP | GPQGARGQPG | 
    650:
    VMGFPGPKGA | NGEPGKAGEK | GLAGAPGLRG | LPGKDGETGA | AGPPGPSGPA | 
    700:
    GERGEQGAPG | PSGFQGLPGP | PGPPGEGGKQ | GDQGIPGEAG | APGLVGPRGE | 
    750:
    RGFPGERGSP | GAQGLQGPRG | LPGTPGTDGP | KGAAGPDGPP | GAQGPPGLQG | 
    800:
    MPGERGAAGI | AGPKGDRGDV | GEKGPEGAPG | KDGGRGLTGP | IGPPGPAGAN | 
    850:
    GEKGEVGPPG | PSGSTGARGA | PGERGETGPP | GPAGFAGPPG | ADGQPGAKGD | 
    900:
    QGEAGQKGDA | GAPGPQGPSG | APGPQGPTGV | TGPKGARGAQ | GPPGATGFPG | 
    950:
    AAGRVGPPGA | NGNPGPAGPP | GPAGKDGPKG | VRGDSGPPGR | AGDPGLQGPA | 
    1000:
    GAPGEKGEPG | DDGPSGLDGP | PGPQGLAGQR | GIVGLPGQRG | ERGFPGLPGP | 
    1050:
    SGEPGKQGAP | GASGDRGPPG | PVGPPGLTGP | AGEPGREGSP | GADGPPGRDG | 
    1100:
    AAGVKGDRGE | TGALGAPGAP | GPPGSPGPAG | PTGKQGDRGE | AGAQGPMGPS | 
    1150:
    GPAGARGIAG | PQGPRGDKGE | SGEQGERGLK | GHRGFTGLQG | LPGPPGPSGD | 
    1200:
    QGASGPAGPS | GPRGPPGPVG | PSGKDGSNGI | PGPIGPPGPR | GRSGETGPVG | 
    1250:
    PPGSPGPPGP | PGPPGPGIDM | SAFAGLGQRE | KGPDPMQYMR | ADEADSTLRQ | 
    1300:
    HDVEVDATLK | SLNNQIESIR | SPDGSRKNPA | RTCQDLKLCH | PEWKSGDYWI | 
    1350:
    DPNQGCTLDA | MKVFCNMETG | ETCVYPNPAT | VPRKNWWSSK | SKEKKHIWFG | 
    1400:
    ETMNGGFHFS | YGDGNLAPNT | ANVQMTFLRL | LSTEGSQNIT | YHCKNSIAYL | 
    1450:
    DEAAGNLKKA | LLIQGSNDVE | MRAEGNSRFT | YTALKDGCTK | HTGKWGKTVI | 
    1487:
    EYRSQKTSRL | PIIDIAPMDI | GGAEQEFGVD | IGPVCFL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    String:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Collagen alpha-1(II) chain
    Cat.:
    E0572r
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    Packing:
    96T
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    ELISA Kit for Mouse Collagen alpha-1(II) chain
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    MSDS:
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    ELISA Kit for Mouse Collagen alpha-1(II) chain
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    MSDS:
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    Packing:
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    ELISA Kit for Mouse Collagen alpha-1(II) chain
    Cat.:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Collagen alpha-1(II) chain
    Cat.:
    E0572c
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Collagen alpha-1(II) chain
    Cat.:
    U0572c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Collagen alpha-1(II) chain
    Cat.:
    U0572h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Collagen alpha-1(II) chain
    Cat.:
    U0572m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Collagen alpha-1(II) chain
    Cat.:
    U0572b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Collagen alpha-1(II) chain
    Cat.:
    U0572r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    Polyclonal Antibody for Mouse Collagen alpha-1(II) chain
    Cat.:
    P0572Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Collagen alpha-1(II) chain
    Cat.:
    P0572Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Collagen alpha-1(II) chain
    Polyclonal Antibody for Mouse Collagen alpha-1(II) chain
    Polyclonal Antibody for Mouse Collagen alpha-1(II) chain
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    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Collagen alpha-1(II) chain
    Monoclonal Antibody for Mouse Collagen alpha-1(II) chain
    Monoclonal Antibody for Mouse Collagen alpha-1(II) chain
    Monoclonal Antibody for Mouse Collagen alpha-1(II) chain
    Monoclonal Antibody for Mouse Collagen alpha-1(II) chain
    Protein for Mouse Collagen alpha-1(II) chain
    Protein for Mouse Collagen alpha-1(II) chain
    Protein for Mouse Collagen alpha-1(II) chain
    Cat.:
    R0572h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Mouse Collagen alpha-1(II) chain
    Protein for Mouse Collagen alpha-1(II) chain

    R&D Technical Data
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    12% SDS-PAGE analysis

          12% SDS-PAGE analysis

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    Precision
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    Linearity
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    References
    1. 1.
      "Mouse type II collagen gene. Complete nucleotide sequence, exon structure, and alternative splicing."
      Metsaeranta M. , Toman D. , de Crombrugghe B. , Vuorio E.
      J. Biol. Chem.266:16862-16869(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];ALTERNATIVE SPLICING
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 7)
      strain: C57BL/6.
      tissue: Brain.
      tissue: Eye.
      tissue: Olfactory epithelium.
    3. 3.
      "Expression of the mouse alpha 1(II) collagen gene is not restricted to cartilage during development."
      Cheah K.S. , Lau E.T. , Au P.K. , Tam P.P.
      Development111:945-953(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-28;DEVELOPMENTAL STAGE
    4. 4.
      "The mouse Col2a-1 gene is highly conserved and is linked to Int-1 on chromosome 15."
      Cheah K.S. , Au P.K. , Lau E.T. , Little P.F. , Stubbs L.
      Mamm. Genome1:171-183(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-28; 1031-1145 AND 1359-1487
    5. 5.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 597-1487
      strain: C57BL/6J.
      tissue: Head.
    6. 6.
      "Specific hybridization probes for mouse type I, II, III and IX collagen mRNAs."
      Metsaeranta M. , Toman D. , de Crombrugghe B. , Vuorio E.
      Biochim. Biophys. Acta1089:241-243(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1483-1487
    7. 7.
      "A missense mutation in the mouse Col2a1 gene causes spondyloepiphyseal dysplasia congenita, hearing loss, and retinoschisis."
      Donahue L.R. , Chang B. , Mohan S. , Miyakoshi N. , Wergedal J.E. , Baylink D.J. , Hawes N.L. , Rosen C.J. , Ward-Bailey P. , Zheng Q.Y. , Bronson R.T. , Johnson K.R. , Davisson M.T.
      J. Bone Miner. Res.18:1612-1621(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT SEDC CYS-989
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